Say goodbye to untreatable “infections from hell”

0
391

Cutting-edge DNA diagnostics enables your doctor too quickly

Identify and eradicate the exact germ(s) ruining your life

Whether lodged in the urinary tract, respiratory tract, reproductive tract, or elsewhere in or on the body, millions of Americans are living with painful and sometimes life-threatening chronic infections.

These unresolved “infections from Hell” are maddening for patients who must spend their time and money consulting with multiple doctors who prescribe an endless stream of antibiotics and other medications that do nothing to stem inflammation and ease the patient’s pain and discomfort.

“People needlessly suffer with persistent chronic infections because their doctors use 150-year-old culture testing, where samples are placed in petri dishes with the hope that whatever is causing the infection will grow there,” says Rick Martin, CEO of biotech diagnostics lab MicroGenDX. “These traditional culture tests have a 50% chance of showing nothing useful to clinicians – which means the doctor’s diagnosis and the medication prescribed will not be helpful. Tragically, some infective microbes are never diagnosed correctly – leaving the patient with an unresolved lifelong infection that never receives effective treatment.”

Martin says the good news is that MicroGenDX has developed a cutting-edge process to identify, with 99.2 percent accuracy, disease-causing pathogens based on their DNA. The computerized analysis (called NGS or Next Generation Sequencing) rapidly compares millions of DNA fragments found in infected tissue and fluid samples against the genetic sequences of more than 50,000 known bacteria and fungi stored in a database.

“Rather than test for a specific suspected pathogen, a doctor can now simply run a DNA test on the patient’s specimen that will quickly identify all the bacteria and fungi in the sample sent to us from the infected area,” says Martin.

Once the microbe is positively identified by its genetic sequence, the proper antibiotic or antifungal can be prescribed, enabling the patient to begin to recover from infections which may have persisted for years or in some cases decades.

Proper antimicrobial use is also of importance due to the increasing antibiotic resistance that is growing due to the overuse and improper use of antibiotics. Antibiotic resistance is one of the biggest public health challenges of our time. Each year in the U.S., at least 2.8 million people get an antibiotic-resistant infection, and more than 35,000 people die.

Source: CDC Using MicroGenDX testing to get the information needed to proscribe the correct antimicrobial the first time is a key step to fight this growing problem.

“The new DNA testing protocol not only provides life-changing benefits for patients, but it also potentially provides billions in savings for America’s overburdened healthcare system – as multiple doctor visits and countless hours of culture analysis in diagnostic labs will no longer be necessary to cure even the most stubborn infections.”

NGS – Next Generation Sequencing is covered by Medicare and some insurers.

MICROBIAL SPECIES INFECTION STATS:

  • Number of species identified in humans – over 10,700
  • Number of species identified in urine – 5,801
  • Number of species identified in wounds – 5,790
  • Number of species identified in vaginal samples – 1,000
  • Number of species identified in prosthetic joint infections – 3,339
  • Number of fungal species identified in nail samples – 2,986
  • Number of Species in MicroGenDX Database – Over 50,000

SAMPLE INTERVIEW QUESTIONS

  1. Can you explain the traditional procedure used by most doctors for diagnosing and treating infections such as urinary tract infections?
  2. Why does that method (culturing) often fail to produce a good result for the patient?
  3. How does the new DNA diagnostic test work?
  4. Why do you and others consider this procedure to be a major advance in medicine?
  5. Tell us about a few of the more challenging infections resolved by your DNA diagnostic protocol. (NGS – Next Generation Sequencing)
  6. You report that 80% of chronic infections are caused by biofilms. What are biofilms, and does your test detect and accurately identify them?
  7. Can patients order this test (NGS-Next Generation Sequencing) directly from MicroGenDX or should they contact their doctor to request it?
  8. Why isn’t this covered by all insurers?
  9. If you have an infection don’t they just give antibiotics, why doesn’t that work?
  10. This sounds like it makes sense logically, why doesn’t more of medicine use it?
  11. What is stopping more physicians from adopting this?
  12. People are worried about antibiotic resistance, how does this technology play into combating that?
  13. Where can listeners get more information about your company (MicroGenDX) and your DNA testing protocol (NGS – Next Generation Sequencing)?

ABOUT RICK MARTIN, CEO of MicroGenDX

As the former head of Pfizer Pharmaceutical’s Anti-infective Division in Turkey, and later as head of international sales for Pfizer in Europe, Canada, Africa, and the Middle East, Rick Martin has spent decades educating doctors about antibiotics and antifungals and how to effectively use them. He now serves as CEO of MicroGenDX, a diagnostic laboratory providing DNA sequencing and rapid PCR-based microbial testing for clinical applications.